Checkpoint Responses in Cancer Therapy

Publisher: Humana Press
Number Of Pages: 314
Publication Date: 2008-05-01
ISBN-10 / ASIN: 1588299309
ISBN-13 / EAN: 9781588299307
Binding: Hardcover

Product Description:
Extensive research has uncovered a set of molecular surveillance mechanisms – commonly called “checkpoints” – which tightly monitor cell-cycle processes. Today’s anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now promises to uncover a new generation of anticancer drugs with improved therapeutic indices based on their ability to target emerging checkpoint components. Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs.
| Tags: Oncology, Physical Therapy |